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Factor XII (Hageman factor) deficiency
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| Definition: |
This is an inherited disorder that causes prolonged clotting (coagulation) of blood in a test tube without a clinical bleeding tendency, and results from a deficiency of the plasma protein factor XII.
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| Causes, incidence, and risk factors: |
| Factor XII deficiency is a hereditary disorder that is usually found when clotting tests are done for routine screening. It is not associated with abnormal bleeding, and is a rare disorder. |
| Symptoms: |
| There are usually no symptoms. |
| Treatment: |
| Treatment is generally unnecessary. |
| Expectations (prognosis): |
| The outcome is expected to be good, even without treatment. |
| Complications: |
| There are usually no complications. |
| Calling your health care provider: |
| This condition is usually discovered by the health care provider when prolonged clotting is noticed in the process of running other laboratory tests. |
| Prevention: |
| This is an inherited disorder. There is no known way to prevent it. |
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Review Date: 10/14/2001
Reviewed By: Rebecca Elstrom, M.D., Division of Hematology-Oncology, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network.
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