Lyme disease - Borrelia burgdorferi organism
Lyme disease - Borrelia burgdorferi organism
Tertiary Lyme disease
Tertiary Lyme disease
Tick imbedded in the skin
Tick imbedded in the skin

Lyme disease - tertiary

Definition:
A late, persistent inflammatory disease caused by the bacterium, Borrelia burgdorferi, which is transmitted by the bite of a deer tick.

Alternative Names:
Stage 3 Lyme disease; Late persistent Lyme disease; Chronic Lyme Disease

Causes, incidence, and risk factors:

Tertiary Lyme disease occurs months to years after the initial infection (see Lyme disease for more information). Symptoms include skin, neurological, and musculoskeletal manifestations.

Symptoms:

Additional symptoms that may be associated with this disease:

Signs and tests:
  • An ELISA shows antibodies to Borrelia burgdorferi. A Western blot test is done to confirm ELISA results.
  • A spinal tap will be abnormal if central nervous signs are present.
Treatment:

The objective of treatment is to eliminate the infection by antibiotic therapy. A high dose of penicillin or ceftriaxone is usually required in the late stages of the disease to treat the infection.

Expectations (prognosis):

Symptoms of arthritis may fail to resolve with treatment. Other symptoms should improve with treatment.

Complications:
Calling your health care provider:

Call your health care provider if symptoms develop -- particularly if you have had Lyme disease before, or live or travel in high-risk areas.

Prevention:

Early diagnosis and appropriate antibiotic treatment for primary Lyme disease is the most effective way to prevent tertiary Lyme disease.


Review Date: 2/22/2002
Reviewed By: Camille Kotton, M.D., Infectious Diseases Division, Massachusetts General Hospital and Brigham and Women's Hospital, Boston, MA. Review provided by VeriMed Healthcare Network.
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