Common causes of vein inflammation include local irritation (for example, because of an IV line), infection in or near a vein and blood clots.

See the specific disorders associated with thrombophlebitis:

• superficial thrombophlebitis (affects veins near the skin surface)
• deep venous thrombosis (affects deeper, larger veins)
• pelvic vein thrombophlebitis

The following symptoms are often associated with thrombophlebitis:

• tenderness over the vein
• pain in the part of the body affected
• skin redness or inflammation (not always present)

The health care provider makes the diagnosis primarily based on the appearance of the affected area. Frequent checks of the pulse, blood pressure, temperature, skin condition, and circulation may be required.

If the cause is not readily identifiable, tests may be performed to determine the cause, including the following:

• Doppler ultrasound
• Extremity arteriography
• Blood coagulation studies

For more specific recommendations, see the particular condition.

Medications may include analgesics (pain medications), anticoagulants or blood thinners to prevent new clot formation, or thrombolytics to dissolve an existing clot. Nonsteroidal anti-inflammatory medications (NSAIDS) such as ibuprofen may reduce pain and inflammation. Antibiotics are prescribed if infection is present.

Support stockings and wraps may be of benefit in some cases to reduce discomfort. Elevate the affected area to reduce swelling. Keep pressure off of the area to reduce pain and decrease the risk of further damage. Apply moist heat to reduce inflammation and pain.

Surgical removal, stripping, or bypass of the vein is rarely needed but may be recommended in some situations.

Call your health care provider if symptoms indicate thrombophlebitis may be present.

Call your health care provider promptly if you have or suspect you have thrombophlebitis and symptoms do not improve with treatment. Also call promptly if symptoms worsen or if new symptoms occur, such as an entire limb becoming pale, cold, or swollen or if chills and fever develop.