Eye
Eye

Trachoma

Definition:
Trachoma is an eye infection caused by Chlamydia trachomatis, which may result in chronic scarring and blindness if left untreated.

Alternative Names:
Granular conjunctivitis; Egyptian ophthalmia

Causes, incidence, and risk factors:

Trachoma is caused by infection with the bacteria Chlamydiatrachomatis. It has an incubation period of 5 to 12 days and begins slowly as conjunctivitis (irritation near the eye, "pink eye"), which if untreated may become chronic and lead to scarring.

If the eyelids are severely irritated, the eyelashes may turn in and rub against the cornea. This can cause eye ulcers, further scarring, visual loss, and even blindness.

Trachoma occurs worldwide -- primarily in rural settings in developing countries. It frequently affects children, although the consequences of scarring may not be evident until later in life. While trachoma is rare in the United States, certain populations marked by poverty, crowded living conditions, and/or poor hygiene are at higher risk for this illness.

Trachoma is acquired via direct contact with eye or nose-throat secretions from affected individuals or by contact with inanimate objects which are contaminated with these secretions, such as towels or clothes. In addition, certain flies which have fed on these secretions can transmit trachoma.

Symptoms:
Signs and tests:

Trachoma is definitely diagnosed by detection of the organism or antigen in conjunctival scrapings or by isolation of the bacteria in culture.

Treatment:
Systemic therapy with oral antibiotics can prevent long-term complications if used early in the infection. Active antibiotics include erythromycin and its derivatives, or doxycycline. In certain cases, eyelid surgery for lid deformities may be needed to prevent chronic scarring which can lead to blindness if not corrected.
Expectations (prognosis):
Early treatment before the development of scarring and lid deformities has an excellent prognosis.
Complications:
  • scarring of the conjunctiva and cornea
  • lid deformities
  • turned-in eyelashes
  • visual loss -- if severe, may result in blindness
Calling your health care provider:
Call your health care provider if you or your child recently visited an area of the world where trachoma is common and there are symptoms of conjunctivitis.
Prevention:

Trachoma is spread by direct contact with eye, nose, and throat secretions from affected individuals or by contact with objects that may have been in contact with these secretions.

Improved sanitation and avoidance in the use of common toilet articles (e.g., towels) are important measures that will limit the spread/acquisition of trachoma.


Review Date: 8/7/2002
Reviewed By: Camille Kotton, M.D., Infectious Diseases Division, Massachusetts General Hospital and Brigham and Women's Hospital, Boston, MA. Review provided by VeriMed Healthcare Network.
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