Hyperemesis gravidarum

Definition:
The presence of extreme, persistent nausea and vomiting during pregnancy that may lead to dehydration.

Causes, incidence, and risk factors:

The cause of nausea and vomiting during pregnancy is believed to be rapidly rising serum levels of HCG (human chorionic gonadotropin) secreted by the fetus. Increased estrogen levels have also been implicated. Extreme nausea and vomiting during pregnancy may indicate multiple pregnancy or hydatidiform mole (abnormal tissue growth, not a true pregnancy).

Symptoms:
Signs and tests:

Signs of dehydration may occur, including:

Blood tests may be recommended for further evidence of dehydration.

Treatment:

Uncomplicated nausea and vomiting may be treated with dry foods (crackers), small frequent meals, and emotional support. It is important for the pregnant woman to maintain her fluid intake; therefore, fluids should be emphasized during the times of the day when she may feel less nauseated.

Medication to prevent nausea is reserved for cases where vomiting is persistent and of adequate amounts to present potential maternal and fetal risks. Severe cases may require hospitalization with IV fluid administration.

An evaluation to rule out abnormalities of the liver or gastrointestinal tract may be indicated in cases of persistent symptoms.

Psychosocial support is an important part of treatment.

Expectations (prognosis):

Nausea and vomiting usually is worse between 2 and 12 weeks gestation, resolving usually by the 2nd half of a pregnancy.With adequate identification of symptoms and careful follow-up, this should not present serious complications for the infant or mother.

Complications:

Social or psychological problems may be associated with this disorder of pregnancy. If such problems exist, they need to be identified and addressed appropriately.

Calling your health care provider:

Call your health care provider/obstetrician if pregnant and experiencing severe nausea with vomiting.

Prevention:
There is no known prevention.

Review Date: 6/16/2001
Reviewed By: Catherine S. Bradley, M.D., Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network.
A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC's accreditation program is the first of its kind, requiring compliance with 53 standards of quality and accountability, verified by independent audit. A.D.A.M. is among the first to achieve this important distinction for online health information and services. A.D.A.M. is also a founding member of Hi-Ethics (www.hiethics.com) and subscribes to the principles of the Health on the Net Foundation (www.hon.ch).

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2003 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.