The parathyroid glands are located in the throat near the thyroid gland. They secrete parathyroid hormone (PTH), which helps control the body's calcium levels.
A parathyroid biopsy most often is performed as the first part of a surgical procedure to examine and/or remove these glands, usually because of hypercalcemia (increased blood calcium) caused by hyperparathyroidism (increased parathyroid hormone production).
Hyperparathyroidism can be a primary condition (parathyroid hyperplasia) or it can be a secondary condition caused by a tumor of the parathyroid gland.
For the biopsy, you will be under general anesthesia with endotracheal intubation (breathing tube placed in the airway). The physician will make an incision in the lower neck above the sternum. The thyroid gland is identified and may be rotated to enable the parathyroid glands to be located The number and exact location of the parathyroid glands can vary from individual to individual. Usually, there are between three and seven, most commonly four).
A sample may be cut from the parathyroid glands, or an entire gland may be removed. The tissue is sent to the laboratory for examination.
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