A simian crease is a single palmar crease as compared to two creases in a normal palm. Simian crease occurs in about 1 out of 30 normal people, but is also frequently associated with other conditions such as Down syndrome, Aarskog syndrome or fetal alcohol syndrome.

Review Date: 1/9/2002 12:00:00 AM Reviewed By:A.D.A.M. Medical Illustration Team and J. Gordon Lambert, MD, Associate Medical Director; G. Eric Morgan, MS3; RxRemedy

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