Drugs >  Glimepiride
Glimepiride
Pronunciation
Brand Names
Therapeutic Categories
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(GLYE me pye ride)

Brand Names
Amaryl®

Therapeutic Categories
Antidiabetic Agent (Sulfonylurea)

Reasons not to take this medicine

  • If you have an allergy to any sulfonamide, glimepiride, or any other part of the medicine.


What is this medicine used for?

  • This medicine is used to lower blood sugar in diabetic patients who have type 2 diabetes. It can be used alone or in combination with other diabetes medicine.


How does it work?

  • Glimepiride increases insulin secretion from the pancreas. The pancreas is the organ that produces insulin. This medicine may make tissues more sensitive to insulin also.


How is it best taken?

  • Take with the first meal of the day.
  • Follow diet plan and exercise program as recommended by healthcare provider.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible (within 2-3 hours).
  • If later than 2-3 hours, skip the missed one and return to your regular schedule.
  • Do not take a double dose or extra doses.


What are the precautions when taking this medicine?

  • Wear disease medical alert identification for diabetes.
  • If you are 80 years of age or older, you may be more sensitive to low blood sugars.
  • Avoid alcohol intake (includes wine, beer, and liquor).
  • Do not drive if blood sugar has been low. There is a greater risk of an accident.
  • Keep hard candies, liquid glucose, or milk on hand for low blood sugars.
  • Use caution if you have kidney disease. Talk with healthcare provider.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Tell healthcare provider if you are breast-feeding.


What are the common side effects of this medicine?

  • Low blood sugar. This can cause anger, shaking, rapid heartbeats, confusion, sweating. Can be life-threatening if not treated with hard candies, liquid glucose, milk.


What should I monitor?

  • Check blood sugar as ordered by healthcare provider. Call if glucose is less than 80 mg/dL or greater than 250 mg/dL. Bring results to follow-up visits.
  • Watch for low blood sugar. This can cause anger, shaking, rapid heartbeats, confusion, sweating.
  • Watch for high blood sugar. Causes many trips to the bathroom, thirst, and weight loss.
  • Check blood work. Talk with healthcare provider.
  • Follow diet plan and exercise program as recommended by healthcare provider.
  • Have a yearly eye exam and visit to the foot doctor.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Low blood sugar or very high blood sugar.
  • Any rash.


How should I store this medicine?

  • Store in a tight, light-resistant container at room temperature.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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