Cisapride
Pronunciation
Brand Names
Therapeutic Categories
What key warnings should I know about before taking this medicine?
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(SIS a pride)

Brand Names
Propulsid®

Therapeutic Categories
Gastrointestinal Agent, Prokinetic

What key warnings should I know about before taking this medicine?

Although removed from the market in the United States, there may be special cases when you can still get cisapride. Dangerous, fast heartbeats can occur. Tell healthcare provider if you have a history of fast heartbeats, kidney failure, low potassium or magnesium levels, or lung failure. Do not take extra doses. Check all medicines with healthcare provider.


Reasons not to take this medicine
  • If you have an allergy to cisapride or any other part of this medicine.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
  • If you have any of the following conditions: Fast or slow heartbeat, heart disease, hole in the gastrointestinal tract, intestinal blockage, kidney disease, low magnesium levels, low potassium levels, lung failure, severe gastrointestinal bleeding, or severely weakened heart.
  • If you are taking any of these medicines: Amprenavir, bepridil, clarithromycin, erythromycin, fluconazole, indinavir, itraconazole, ketoconazole, miconazole, nefazodone, ritonavir, sparfloxacin, terodiline, troleandomycin, certain drugs used for a fast heartbeat, certain schizophrenia medicines, or certain depression medicines.

  • What is this medicine used for?
  • This medicine is used in patients receiving tube feedings who have high residuals.
  • This medicine is used to treat heartburn.
  • This medicine is used to treat severe constipation.
  • This medicine is used to treat poor stomach emptying.

  • How does it work?
  • Cisapride increases gastric emptying and movement through the gastrointestinal tract.

  • How is it best taken?
  • Take this medicine 15-30 minutes before meals and at bedtime.
  • A liquid (suspension) is available if you cannot swallow pills. Shake well before use. Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine is given.

  • What do I do if I miss a dose?
  • Take a missed dose as soon as possible.
  • If longer than 1 hour, skip the missed dose and return to your regular schedule.
  • Do not take a double dose or extra doses.
  • Do not change dose or stop medicine. Talk with healthcare provider.

  • What are the precautions when taking this medicine?
  • If you have a weakened heart, talk with healthcare provider.
  • Check medicines with healthcare provider. This medicine may not mix well with other medicines. Combinations could be life-threatening.
  • Avoid alcohol, smoking, elevate head of the bed, avoid large meals before bed, lose weight, and avoid fatty foods, chocolate, caffeine, or grapefruit and grapefruit juice.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Tell healthcare provider if you are breast-feeding.

  • What are the common side effects of this medicine?
  • Headache. Mild pain medicine may help.
  • Belly pain.
  • Diarrhea.

  • What should I monitor?
  • Change in condition being treated. Is it better, worse, or about the same?

  • Reasons to call healthcare provider immediately
  • If you suspect an overdose, call your local poison control center immediately or dial 911.
  • Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
  • Fast heartbeat.
  • Severe dizziness or passing out.
  • Severe diarrhea.
  • No improvement in condition or feeling worse.

  • How should I store this medicine?
  • Store at room temperature.
  • Protect tablets from light.
  • Protect tablets from moisture. Do not store in a bathroom or kitchen.

  • General statements
  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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